Disseminated toxoplasmosis, resulting from infection of allograft, after orthotopic liver transplantation: usefulness of quantitative PCR.

نویسندگان

  • Francoise Botterel
  • P Ichai
  • C Feray
  • P Bouree
  • F Saliba
  • R Tur Raspa
  • D Samuel
  • S Romand
چکیده

Disseminated toxoplasmosis is a life-threatening disease in liver transplant recipients that can result from an organ-transmitted infection. We report here a case of fatal disseminated toxoplasmosis after orthotopic liver transplantation from a seropositive donor (immunoglobulin G [IgG](+) and IgM(-)) in a patient who was nonimmune for toxoplasmosis prior to transplantation. Quantitative PCR analyses of various clinical specimens, including serum samples, appeared retrospectively to be a valuable diagnostic tool that might guide therapeutic attitudes.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 40 5  شماره 

صفحات  -

تاریخ انتشار 2002